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Accelerate your drug discovery programme with the Ectocellect human cell surface receptor screening platform

The Problem

Cell surface proteins are common drug targets but are biochemically challenging to work with because they are embedded in lipid membranes

 This complicates drug development processes such as antibody deconvolution and on-target specificity testing

Our Solution

At Ectocellect, we have developed a scalable assay platform that confidently identifies extracellular protein interactions with unmatched precision. Our high-quality genome-scale human arrays contain entire receptor ectodomains that are validated and functional.

Applications

Boost your research using the Ectocellect receptor array for:

Drug and antibody off-target screening

Cost effectively test for relevant off-target effects during early-stage lead selection.

Target deconvolution

Identify the targets of functional antibodies of unknown specificity.

Extracellular protein interactions

“De-orphanise” ligands and receptors.

Autoantigens

Discover the targets of autoantibodies

FAQ

How much protein do I need to provide?

Antibodies should be provided at a concentration ~1 mg ml with no less than 60 micrograms. 

 

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