Receptor Discovery and Deorphanization
A trusted platform to characterize 'orphan' ligands and receptors with unknown binding profiles
Identify novel receptors for orphan ligands
Host-pathogen interactions including virus receptors, microbiome, and parasites
Ectocellect receptor array detects even very weak interactions (KDs < 10 µM), with low false positive and false negative rates
Receptor discovery case study
The Ectocellect human receptor array was used to identify direct interactions with human host receptors for a previously-uncharacterized parasite immunoregulatory ligand. Specificity is demonstrated here as the ligand identified five different members of the same human receptor family.
Applications
Boost your research using the Ectocellect receptor array for:
Therapeutic antibody specificity testing
Cost effectively test binding specificity of antibodies and AI-designed binders.
Antibody target deconvolution
Identify the targets of functional antibodies of unknown specificity.
Autoantibody target discovery
Discover the targets of patient autoantibodies
