Receptor Discovery and Deorphanisation
A trusted platform to deorphanise ligands and receptors
Identify novel receptors for orphan ligands
Host-pathogen interactions including virus receptors, microbiome, and parasites
Ectocellect receptor array detects even very weak (KDs ~ 10µM) with low false positive and false negative rates
Deorphanisation case study
The Ectocellect human receptor array was used to identify direct interactions with human host receptors for a parasite immunoregulatory ligand. Specificity is demonstrated here as the ligand identified five different members of the same human receptor family.
Applications
Boost your research using the Ectocellect receptor array for:
Therapeutic antibody specificity testing
Cost effectively test binding specificity of antibodies and AI-designed binders.
Antibody target deconvolution
Identify the targets of functional antibodies of unknown specificity.
Autoantibody target discovery
Discover the targets of patient autoantibodies
