Antibody target deconvolution and autoantigen discovery
Discover the binding target of your antibodies
Useful for antibodies of functional interest identified by B-cell sequencing or AI-designed affinity binders
Scalability: cost effectively test 10s to 100s of antibodies
Only small amounts (50 micrograms) of antibody required
Case Study: deconvoluting the target identity for a disease-associated antibody
A disease-associated B-cell was isolated, receptor sequenced, and resulting antibody recombinantly expressed as a human IgG1. The antibody was tested on the Ectocellect array and its target identified.
Applications
Boost your research using the Ectocellect receptor array for:
Therapeutic antibody specificity testing
Cost effectively test binding specificity of antibodies and AI-designed binders.
Receptor deorphanisation
Discover new receptors and ligands.
Autoantibody target discovery
Discover the targets of patient autoantibodies
