Antibody target deconvolution and autoantigen discovery
The majority of functional epitopes are conformational requiring natively folded proteins
Proteins on the Ectocellect array are folded and active
Proteins are kept in aqueous solution throughout, avoiding damaging phase changes and excessive oxidation which can lead to protein inactivation
Only small amounts of antibody (100 micrograms) or sera (100 microlitres) are needed for testing
